Domestication is a topic that has interested evolutionary biologist for hundreds of years since Darwin first described this phenomenon in the first chapter of seminal work. Within the last 10 years, increases in genomic technologies have allowed researchers to begin to tease apart the genomic basis of domestication events in several species of both animals and plants. Craig’s interest in domestication lies not only with domestic phenotypes, but the rate of phenotypic change that selection can induce within a short period of time. Craig has focused his interest in domestication on the model organism Drosophila melanogaster.Although anecdotal evidence of behavioral differences in laboratory strains existed, Craig was able to use a computer tracking system to empirically identify differences in locomotor activity. Using population genomic datasets from Dmel throughout the world, Craig has identified several signatures of selection found within the genome of laboratory strains of Dmel.